Grantee: Boston Children’s Hospital
Project Title: The Bennett C. Endres Fellowship/Specialized Fellowship Training in the Neuropathology of Sudden Unexpected Death in Pediatrics (SUDP)
Principal Investigator: Hannah C, Kinney, MD
The differential diagnosis of sudden and unexpected death in pediatrics (SUDP) due to disorders of the nervous system is large and complex, and requires specialized training in neuropathology to learn to become proficient. Given the enormity and complexity of the clinical problem of SUDP, knowledgeable neuropathologists versed in the many different aspects of this field are urgently needed. The CJ Foundation for SIDS has established, with the Endres family, the Bennett C. Endres Fellowship in Sudden Unexpected Death in Pediatrics (SUDP), a neuropathology training program. Dr. Jane B. Cryan, Department of Neuropathology, Beaumont Hospital, Dublin, Ireland, is this year’s recipient of this important fellowship. A major purpose of this training period is to “capture” this resident early in his/her training for a life-long career in clinical service and research in the neuropathology of SUDP, and to lay the foundation for this career.
Dr. Cryan is an anatomic pathologist with specialized training in neuropathology. She is board certified in neuropathology. She trained for two years in the combined neuropathology training program at Boston Children’s Hospital and Brigham and Women’s Hospital. One of these years was spent doing SUDP research in Dr. Kinney’s laboratory. Her manuscripts with the Kinney laboratory are in preparation, with one completed and published January 2015 (Kinney HC, Cryan, JB, Haynes RL, Paterson DS, Haas EA, Mena OJ, Minter M, Journey KW, Trachtenberg FL, Goldstein RD, Armstrong DD. Dentate gyrus abnormalities in sudden unexplained death in infants: Morphological marker of underlying brain vulnerability. Acta Neuropathol 2014; 129: 65-80).
During her time in Dr. Kinney’s laboratory, Dr. Kinney recognized the special gifts in neuropathology of Dr. Cryan, as a pathologist sharp in diagnostic skills and judicious in case synthesis and interpretation. Most of all, Dr. Kinney appreciated Dr. Cryan’s deep kindness and concern for children, and her dedication to understanding sudden death in children in order to find the ways to prevent it. While Dr. Cryan is in Dublin, extensive plans for slide review and teaching have been made to overcome the barrier of long distance. In addition, the fellowship will allow Dr. Cryan two trips a year to Boston for direct laboratory meaning. It is also seen as positive that a trainee of the Endres Fellowship be an international student to ensure committed pathologists to SUDP here and abroad.